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The Initiative

Prof. Jean-Charles Fruchart

Prof. Jean-Charles Fruchart


Pasteur Institute,
Lille, France

Current position

Jean-Charles Fruchart is:
•Professor in Pasteur Institute of Lille and University of Lille, France
•Past President of the International Society of Atherosclerosis
•President – Founder of Genfit
•President of the Scientific Council – Founder of Cardialpha
•President of Foundation “Coeur et Artères”

Professional Associations

•1991 Member of the Academy of Medicine
•1994-2003 Paris President of the Association for Research on Cholesterol (ARCOL)
•1994 Chairman for the European Atherosclerosis Society Meeting
•1995 Member of the Academy of Pharmacy, Paris, France
•1997 Scientific Chairman of the International Atherosclerosis Society Meeting
•1997-2000 President of the Scientific Council of Lille University, France
•1997 Visiting Professor of the University of Concepcion, Chili
•2000 Secretary of the International Society of Atherosclerosis
•2003-2006 President of the International Task Force for Prevention of Coronary Heart Disease

Professor Jean-Charles Fruchart was initiator and chairman of the Metabolic Syndrome, Diabetes and Atherosclerosis congress in 2002, 2004, 2006, 2007 and 2008

Professor Jean-Charles Fruchart is member of the editorial boards of several scientific journals including Nature Medicine, Journal of Clinical Investigation, Arteriosclerosis, Thrombosis and Vascular Biology, Journal of Biological Chemistry, Journal of Lipid Research, Atherosclerosis, etc.


1994 Great Gold Medal of Pasteur Institute award
1995 Chevalier de la Légion d'Honneur, France
1997 Honoris Causa Doctor of the University of Buenos Aires, Argentina
1998 Officier des Palmes Académiques, France
1998 Grand Prix Kuhlmann, Sciences, Agriculture and Arts Society of Lille, France
1998 Prix "Galien" of Pharmaceutical Research, France
2003 Honoris Causa Doctor of the University of Bucharest, Romania
2003 Gold Medal of Foundation Giovanni Lorenzini award
2003 Officier de la Légion d’Honneur, France
2008 Anitschkow Prize


Professor Jean Charles Fruchart scientific interest was initially focused on clinical biochemistry of lipoproteins, but progressively shifted towards lipoprotein metabolism and atherosclerosis. Recently, his group is involved in the study of the transcription factors regulating the metabolism of lipoproteins and discovered the molecular mechanism of action of fibrates through activation of PPAR-alpha.