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The Initiative

Prof. Jorge Plutzky

Prof. Jorge Plutzky
Harvard Medical School,
Boston, MA, USA
Short Narrative Biography

Jorge Plutzky, MD, is the Director of the Vascular Disease Prevention Program, which includes the Lipid/Prevention Clinic, at Brigham and Women’s Hospital, a major teaching affiliate of Harvard Medical School. Dr. Plutzky is also an Associate Professor of Medicine at Harvard Medical School and directs a basic science laboratory that investigates mechanisms linking atherosclerosis to metabolic disorders like dyslipidemia, diabetes and obesity. This work focuses on the transcriptional regulation of vascular responses through nuclear receptors like PPARs and RXRs. Dr. Plutzky's expertise in the intersection of PPARs, dyslipidemia, atherosclerosis, and diabetes is widely renowned, as evident in his role as a prior advisor to the ENdocrine and Metabolism Committee of the Food and Drug Administration. Dr. Plutzky is a highly sought-after lecturer nationally and internationally. Widely published in these areas in both clinical and basic science journals, Dr. Plutzky and his laboratory have received several major research awards including the Klenk Lecture from the University of Cologne, the Tucker Collins Lecture from Harvard Medical School and The Eugene Braunwald Teaching Award from the Brigham and Women’s Hospital. He is a manuscript reviewer for many medical journals, including Circulation, the Journal of Clinical Investigation, and New England Journal of Medicine. His trainees have been recipients of numerous research and career development awards as well.

Dr. Plutzky is a Fellow of the American College of Cardiology (ACC) and a member of the American Society for Clinical Investigation. He also serves as an Outside Reviewer for the National Heart Lung Blood Institute Program Project Grants. Dr. Plutzky is an active volunteer with the American Heart Association and the American Diabetes Association. He serves on the Scientific Committee of the Sarnoff Foundation.

Dr. Plutzky received his Bachelor of Arts degree With Highest Honors from the University of Virginia, Charlottesville and his MD from the University of North Carolina School of Medicine in Chapel Hill, which included a research fellowship at the National Institutes of Health. He completed his internship, residency in internal medicine, and cardiology fellowship all at Brigham and Women’s Hospital in Boston, during which time he was also a Chief Medical Resident at West Roxbury Veteran’s Administration Hospital. He also completed a research fellowship at the Massachusetts Institute of Technology during his cardiology fellowship.