Chronic kidney disease (CKD) is increasingly recognized as a worldwide health concern. Whereas there has been a general decline in rates of death and disability-adjusted life years due to non-communicable diseases, such favourable trends do not exist for CKD.
With the escalating pandemics of obesity and diabetes, as well as aging societies, CKD now affects about 11-15% of people globally. While type 2 diabetes mellitus (T2DM) is a major risk factor for CKD, non-diabetic patients are also at risk. Thus, CKD represents an important unmet clinical need warranting urgent action. ...
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