Recent publications on Residual Risk

The ratio of serum triglycerides to high-density lipoprotein cholesterol (TG/HDL-C) may have potential in estimating the risk of sleep apnoea syndrome, according to this study in non-overweight Japanese men. This cross-sectional study included 1,528 men aged 30-69 years being evaluated for sleep apnoea syndrome, diagnosed as a 3% oxygen desaturation index (ODI) of ?15 events/hour. In total, 241 were diagnosed with sleep apnoea syndrome, independent of conventional risk factors, such as elevated body mass index (BMI). In subjects with a BMI <25 kg/m2, the TG/HDL-C ratio was significantly and positively associated with sleep apnoea syndrome; this was not the case in those with a BMI ?25 kg/m2. The risk of sleep apnoea syndrome was 2-fold higher in individuals with an elevated TG/HDL-C ratio and BMI <25 kg/m2, driven by high triglycerides (multivariable adjusted odds ratio per Log TG-HDL: 2.03, 95 % CI 1.36-3.03). br> 
Taken together, these findings suggest that the TG/HDL-C ratio could have potential in estimating the risk of sleep apnoea syndrome in these individuals, although further study is also merited.