Recent publications on Residual Risk

Serum levels of C-peptide, an important risk factor for cardiovascular disease, are known to increase with age. This population-based cross-sectional study showed a strong association between serum C-peptide and elevated triglycerides and low plasma concentration high-density lipoprotein cholesterol (HDL-C) suggesting that C-peptide may be implicated in the residual cardiovascular risk associated with atherogenic dyslipidaemia in the elderly.
 
The study included 3,091 elderly subjects aged ?65 years. Serum triglycerides and HDL-C levels were significantly associated with changes in serum C-peptide levels, independent of insulin levels. Additionally, there was evidence of a significant dose-response association in both men and women.