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At 6 months, the achieved EPA/AA ratio was more reliable as an independent and significant predictor of reduction in non-high-density lipoprotein cholesterol (non-HDL-C), a measure of total atherogenic lipoproteins cholesterol load, than the absolute change in the EPA/AA ratio. There were also significant negative correlations between the baseline level and absolute change in non-HDL-C and triglyceride-rich lipoproteins. The authors concluded that the achieved EPA/AA ratio could be useful in risk stratification in statin-treated patients with a high non-HDL-C level.