Recent publications on Residual Risk

This Chinese study highlights the importance of triglycerides and high-density lipoprotein cholesterol (HDL-C), components of atherogenic dyslipidaemia, as well as apolipoprotein B (apoB) levels as independent predictors of coronary heart disease (CHD) in individuals referred for coronary angiography. This cross-sectional study included 1,941 patients of whom 1,363 patients had confirmed evidence of CHD. After adjustment for age, sex, body mass index, diabetes, hypertension, smoking and alcohol intake, in nonstatin users there was an independent association between triglycerides, HDL-C and apoB levels and incident CHD (p for trend = .001, .005, and .003, respectively). Given the relatively high prevalence of hypertriglyceridaemia and low HDL-C concentration in this region (both lipid abnormalities were observed in 22% of patients in this study), the study highlights the need to consider appropriate lipid-modifying strategies beyond low-density lipoprotein cholesterol to reduce incident CHD.