Recent publications on Residual Risk

In the Spanish healthcare setting, the polypill (aspirin 100 mg, atorvastatin 20 mg, ramipril 10 mg) is a cost-effective approach to reducing residual cardiovascular risk in adults with a history of myocardial infarction, compared with individual monotherapies. Using Markov modelling, use of the cardiovascular polypill instead of its monocomponents would avoid 46 nonfatal and 11 fatal cardiovascular events per 1000 patients treated over a 10-year period. Moreover, this analysis showed that the polypill would be a cost-effective strategy compared with multiple monotherapy at a willingness-to-pay threshold of 30 000 euros per quality-adjusted life year.